Nature and nurture in vitamin B12 deficiency.
نویسندگان
چکیده
We report on a child in whom severe nutritional vitamin B12 deficiency was exacerbated by a genetic impairment of the folate cycle, causing reduced CSF concentrations of the methyl group donor 5-methyltetrahydrofolate. Some patients with vitamin B12 deficiency may benefit from high dose folic acid supplementation, even if plasma concentrations are high.
منابع مشابه
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ورودعنوان ژورنال:
- Archives of disease in childhood
دوره 87 1 شماره
صفحات -
تاریخ انتشار 2002